Melatonin evidence, 2013

Ferracioli-Oda E, Qawasmi A, Bloch MH, PLoS ONE, 2013 — meta-analysis of melatonin and sleep outcomes

Grade
Design
meta analysis
Year
2013
Participants
1683
Ingredient
Melatonin
Goal
Sleep

Effect

Across 19 RCTs, melatonin shortened time to fall asleep by ~7 minutes, added ~8 minutes of total sleep, and improved rated sleep quality versus placebo.

Limitations and notes

Effects are modest in absolute minutes but consistent across trials.

doi.org/10.1371/journal.pone.0063773

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