Vitamin D3 evidence, 2019
Manson JE, Cook NR, Lee IM, et al., New England Journal of Medicine, 2019 — VITAL trial of vitamin D3 2000 IU/day
- Grade
- Design
- rct
- Year
- 2019
- Participants
- 25871
- Ingredient
- Vitamin D3
- Goal
- Heart & metabolic
Effect
In adults not selected for low vitamin D status, 2000 IU/day did not change major cardiovascular event rates over a median 5.3 years.
Limitations and notes
A high-quality null: why we frame vitamin D as status correction, not broad protection.